From: Gunther.Kern@astrazeneca.com
  To  : dyche@itsa.ucsf.edu, rasmb@bbri.harvard.edu
  Date: Wed, 11 Apr 2001 23:11:54 +0200

RE: global nonlinear fitting

There is a program called Grafit which is commercially available. I do not
know the price for academic use but I like the program due to its excellent
fitting interface, good documentation and good support. Their website is
www.erithacus.com

Hope that is helpful

-----Original Message-----
From: R Mullins [dyche@itsa.ucsf.edu]">mailto:dyche@itsa.ucsf.edu]
Sent: Wednesday, April 11, 2001 4:36 PM
To: rasmb@bbri.harvard.edu
Subject: global nonlinear fitting



Does anybody know of a good, inexpensive software package to do 
global, nonlinear least squares fitting for systems of ordinary
differential equations? We have been using KINSIM and FITSIM for 
years but now I think it's time to move on. FITSIM doesn't have 
the world's most user frienldy interface and isn't very numerically
stable, especially when fitting multiple parameters. Our preferred
operating system is LINUX. 

Thanks,

Dyche

_________________________________________________
Dyche Mullins
Dept. Cell. and Molec. Pharmacology
Health Sciences East, Rm. 1001E
University of California, School of Medicine
513 Parnassus Ave.
San Francisco, CA
94143

Phone: (415)502-4838
Lab:   (415)514-0133
Fax:   (415)476-5233