From: Dr DJ Scott <djs17@york.ac.uk>
  To  : rasmb@alpha.bbri.org
  Date: Tue, 7 Aug 2001 11:43:16 +0100 (BST)

Membrane proteins

Hello all
I wish to do AUC on a (possibly) tetrameric membrance protein. The catch
is that the detergent has to be at a conc around the CMC so there will be
lots of micelles there.

Can AUC give any Mwt or shape info. in these circumstances? I seem to
remember previous emails on the subject of density matching, or am I in a
no-win situation?

Thanks in advance

Dave Scott.

Dr. David J. Scott
York Structural Biology Laboratory
Department of Chemistry
University of York
YORK. North Yorkshire. Y010 5DD
Phone: +44 1904 432590
Fax:   +44 1904 410519
Email: djs17@york.ac.uk
Home Page: www-users.york.ac.uk/~djs17

PLEASE NOTE: FROM 1ST SEPT NEW ADDRESS: DEPT. BIOCHEMISTRY, SCHOOL OF
MEDICAL SCIENCES, UNIVERSITY OF BRISTOL, UNIVERSITY WALK, BRISTOL. BS8
1QD. UNITED KINGDOM.