From: John Correia <jcorreia@biochem.umsmed.edu>
  To  : HOLLADAYL@aol.com
  Date: Tue, 02 May 2000 10:23:42 -0600

parameter correlations

Les

Brad Charies & I published a review on analysis of neighbor exclusion data
that includes parameter correlation plots; they're never linear, often
highly curved and often not correlated - I know Joe Beecham has done
similar analysis in other systems and he refers to the local slope as the
local correlation coefficient.  I agree sed equil data seldom exhibits
complicated parameter correlations (knock on something).....

CORREIA, J.J. and J.B. Chaires  (1994) "Analysis of Drug-DNA Binding
Isotherms: A Monte Carlo Approach",  in Numerical Computation Methods,
Part B, (Ed. L. Brand and M.L.Johnson) Methods in Enzymology, vol 240,
593-614.


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 Dr. John J. "Jack" Correia
 Department of Biochemistry
 University of Mississippi Medical Center
 2500 North State Street
 Jackson, MS  39216
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 email address: jcorreia@biochem.umsmed.edu     
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 dept homepage location:   
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