From: Peter Schuck <pschuck@helix.nih.gov>
  To  : rasmb@alpha.bbri.org
  Date: Wed, 05 Apr 2000 16:51:48 -0700

postdoctoral position in physical biochemistry

Dear Colleagues,

I would appreciate if you could circulate the following postdoctoral
position announcement in your department: 


The Molecular Interactions Resource of the Division for Bioengineering and
Physical Science (DBEPS), Office of Research Services, National Institutes
of Health, invites applications for a post-doctoral position for the
training in the biophysical characterization of reversible interactions of
biomolecules.  
	The techniques applied in the Resource are analytical ultracentrifugation,
surface plasmon resonance biosensing, dynamic light scattering, and
isothermal titration microcalorimetry.  Possible projects include the
application of these biophysical techniques to the characterization of
interacting protein system in collaboration with an intramural NIH
laboratory, and the development and application of new methods, with
emphasis is in (1) the mathematical modeling of sedimentation velocity and
dynamic light scattering data for size-distribution analysis of
macromolecules; and (2) experimental configurations for surface plasmon
resonance biosensing (immobilization, sample delivery methods), and
strategies for the data analysis.  The development of other methodology for
protein interactions in solutions or at surfaces is possible.  The
Molecular Interactions Resource offers a highly interdisciplinary
environment, since our goal is the conduct of collaborative research with
biomedical laboratories at NIH.  Current biological systems studied include
the interactions of cell surface receptors, viral proteins, and others.
Excellent additional biophysical and bioengineering expertise is available
from other DBEPS Resources in optical instrumentation design, imaging,
electron microscopy, microanalytical immunochemistry, and drug delivery.
	Candidates should have a Ph.D. in biophysics, biochemistry, or a related
discipline, and experience in laboratory techniques for proteins
(purification, conjugation, chromatography). Familiarity with methods of
physical biochemistry, expertise in programming, and/or strong mathematical
skills are a plus.  Applicants should send a CV including publication list
and references to Dr. Peter Schuck, National Institutes of Health, Bldg.
13, Room 3N17, 13 South Drive, Bethesda, MD 20892, USA.  Fax (301)
496-6608, email: pschuck@helix.nih.gov. 




***********************************************************
Peter Schuck, PhD
Molecular Interactions Resource
Division of Bioengineering and Physical Science, ORS
National Institutes of Health
Bldg. 13 Rm. 3N17
13 South Drive 
Bethesda, MD 20892 - 5766
Tel: (301) 435-1950
Fax: (301) 496-6608
email: Peter_Schuck@nih.gov
***********************************************************