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  From: Olwyn Byron <o.byron@bio.gla.ac.uk>
  To  : rasmb@alpha.bbri.org
  Date: Wed, 8 Mar 2000 18:01:48 +0000

Postdoctoral Position Available Now in Scotland

Postdoctoral Position Available Now in Scotland

University of Glasgow (http://www.gla.ac.uk)

Institute of Biomedical and Life Sciences (http://www.gla.ac.uk/Acad/IBLS/)
Division of Infection and Immunity (http://www.gla.ac.uk/ibls/II/index.html)

Postdoctoral Research Technologist

"Measurement of biomolecular interactions and conformational changes in
solution with analytical ultracentrifugation"

Starting salary: £16,286 - £20,811 (£1 ‰ $1.59 at 29.02.00).

The appointee will be working in the group of Dr Olwyn Byron
(http://www.gla.ac.uk/Acad/IBLS/II/ob/resint.htm) whose laboratory is
currently equipped with a Beckman XL-A and a Spinco Model E.
The post is funded by the Wellcome Trust (http://www.wellcome.ac.uk/) as
part of the consolidation of an analytical ultracentrifuge (AUC) facility
for the University of Glasgow (and external collaborators).
Included in the award is provision for a new AUC which will be purchased
shortly.

The person appointed will be responsible for the co-ordination and
execution of 4 projects in collaboration with the following scientists at
Glasgow University:

Interactions of pneumolysin with itself and the host immune system
Professor Tim Mitchell
http://www.gla.ac.uk/Acad/IBLS/II/tjm/tjm.htm

Protein-protein and protein-lipid interactions that stabilise myelin sheath
Dr Andy Freer
http://www.chem.gla.ac.uk/~andy/andy.html

Low resolution structural characterisation of filarial nematode
excretory-secretory glycoprotein ES-62
Dr Maggie Harnett
http://www.gla.ac.uk/Acad/Immunology/maggie.htm

Self-, hetero- and ligand-binding interactions of novel parasitic nematode
lipid binding proteins
Professor Malcolm Kennedy
http://www.gla.ac.uk/Acad/IBLS/II/mwk/resint.htm

The ideal applicant will have experience of analytical ultracentrifugation,
and perhaps small-angle X-ray and/or neutron scattering and should be
conversant with other biophysical techniques for macromolecular
characterisation. Full training will be given in areas where the successful
applicant's experience is deficient.
Ideally applicants should also have experience in protein over-expression
and purification, although the systems to be characterised in this project
have already been developed and fine-tuned. Again, training in this area
can be given if necessary. The appointee will be numerate, computer
literate, motivated and able to work without close supervision.

The University of Glasgow, founded in 1451, is the second oldest University
in Scotland and the fourth oldest in Britain. The magnificent Main Building
of the University, designed in Gothic style by Sir George Gilbert Scott, is
one of the city's best known landmarks
(http://www.gla.ac.uk/general/Pictures/index.html). The University has been
on this site since 1870 when it moved from the city centre. Nowhere else in
Scotland is quite like Glasgow, Scotland's largest city
(http://www.gla.ac.uk/homepages/visitors/glasgow.html). It radiates
confidence and friendliness in a down-to-earth way and, for its latitude,
benefits from a mild (if somewhat moist!) climate.

The post is of 36 months' duration and available from 1 July 2000.
Informal enquiries are welcome and should be directed to Olwyn Byron:
tel +44 (0)141 330 3752 or e-mail o.byron@bio.gla.ac.uk.

Applications, including a full CV and the names and (e-mail) addresses of
two referees should be sent Dr Olwyn Byron, Division of Infection and
Immunity, Joseph Black Building, University of Glasgow, Glasgow, G12 8QQ,
Scotland, UK.
Applications by e-mail (as attached Word or rtf documents are welcome
provided they are backed-up by a postal application).

Closing date: 31 March 2000.


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