From: Hiroshi Fujita <lvl79@mbox.kyoto-inet.or.jp>
  To  : rasmb@alpha.bbri.org
  Date: Thu, 09 Sep 1999 12:44:37 +0900

Re: Significance?

Dear all,
The question raised by J. Mackay and commented by some in the last few 
days is an old theme that has troubled many ultracentrifuge people, yet 
found no definitive answer. I put my rather pessimistic view on it in my book 
(D. The Uniqueness problem , pp 413-416, Foundations of ultracentrifugal 
analysis, Wiley, 1975). Probably, it is my friend K. E. Van Holde who paid the 
most serious attention to this theme through a number of his 
excellent sedimentation equilibrium studies on associating biological 
macromolecules. I hope more intensive discussions will take place in this 
forum to clarify  the scope and imitations of ultracentrifugal methods, 
thereby we can more firmly grasp  what  may or may not be demanded for 
the ultracentrifugal characterization of chemically reacting systems.　

Sincerely,

Hiroshi Fujita

Hiroshi Fujita
35 Shimotakedono-Cho, Shichiku, Kita-Ku
Kyoto,　Japan
Phone/Fax：075-491-2061
e-mail:lvl79@mbox.kyoto-inet.or.jp