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  From: John Philo <>
  To  :
  Date: Mon, 27 Jul 1998 12:13:16 -0700

RE: using SVEDBERG with interference


Sorry, the current release of my SVEDBERG program does not work well with
interference data because (1) the zero offset varies from scan to scan,
the baselines are not flat, and (3) there are sometimes jumps of an
number of fringes between scans.

I have solved all these problems and a new version is out for beta
I hope that version will be released around the time of the Beckman
In the meantime I recommend using the DCDT method with interference data.

John Philo

-----Original Message-----
From: Arturo J. Morales []">]
Sent: Monday, July 27, 1998 11:10 AM

Hello all!,

I'm using the Svedberg prg to look at some sedimentation data. I've used
before to look at absorbance data, but this time I have to look at
interference scans...

My scans move up and down quite a bit (which I'm assuming is normal, this
is my first time using Interference) and I read that the prg will take
into account, but when it comes time to display the residuals, fits and
scans, they are all over the place (I cannot superimpose) Is there a
preffered way to do this? I think I can manually edit the scans, but I
know if there is a way to do it in the prg.



     Arturo J. Morales    (RPI
   Department of Biology - Massachusetts Institute of Technology &
  Skaggs Institute for Chemical Biology - Scripps Research Institute

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