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From: Jack Correia <jcorreia@umsmed.edu>
To : Jim Cole <jim_cole@merck.com>
Date: Thu, 2 Nov 1995 17:23:04 -0600
Re: Nonideality
Jim,
You appear to have ruled out the obvious sources. Is M1 a constant
in your fitter or a variable? Would errors in M1 or sigma1, ie. possibly
due to vbar errors as well, show up as a poor fit that requires B? How
about low concentrations of inactive monomers! Wouldn't that show up as a
decrease of MWapp at higher loads and thus look like B? Alan Minton has a
program that will allow for inactive species in an associating system. [I
presume the system is 99% what you think it is with no smaller species.]
Try it and let us know if it helps or works?
|-------------------------------------------------------|
| Dr. Jack Correia |
| Department of Biochemistry |
| Univ. of Miss. Medical Center |
| 2500 N. State St. |
| Jackson, MS 39216 |
| (601) 984-1522 |
| fax (601) 984-1501 |
|-------------------------------------------------------|
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