From: Richard Thomas (Luisi) <rthomas@ifp.mat.ethz.ch>
  To  : rasmb@bbri.eri.harvard.edu
  Date: Tue, 21 Mar 95 18:34:36 +0100

               THE PROTEIN SOCIETY: FIRST EUROPEAN SYMPOSIUM . FINAL
                                                                                                      ANNOUNCEMENT

        The full programme for the 1st European Symposium of the Protein Society
(Davos, Switzerland, 28th May-1st June) has just been finalized. An analytical
ultracentrifuge workshop has been organized as part of the symposium and will take
place on Tuesday 30th May. Five speakers have been invited and there will be
opportunity for discussion and posters. The full programme for the workshop is
given below together with that for the Protein Symposium for 30th May. There is stll
time to submit posters which will be dealt with on a first-come-first-served basis -
please send abstracts to me immediately

Scientists attending the symposium will be able to participate in the workshop free
of charge. There will also be no fee for anyone wishing only to attend the workshop
. A reduced fee of SFr140.00 ($100.00) will be charged for one-day registration on the
30th May, permitting full participation in the symposium proceedings for that day
alone. All those interested in attending the workshop are, however, requested to
register, for organizational purposes. If you have not, as yet, received the requisite
form please contact me and I will send you a copy. The form should be returned no
later than 30th April. If you would like to attend the entire symposium please contact
(Europe) Symposium Secretariat, Inst. of Biochemistry III, ETH-Zentrum,
Universittsstr. 16, CH-8092 Z
rich, (US & overseas) The Protein Society Meeting
Office, 9650 Rockville Pike, Bethesda, MD 20814-3998, USA.


Program Tuesday. 30th May

Session 3: Protein folding including Assisted Protein Folding

08.30   Mechanisms and catalysts of protein disulphide bond formation
        Thomas Creighton

09.00   Pathways of protein folding
        Alan Fersht


Session 4: Methods in Protein research

09.30   Characterization of peptides associated with class I MHC molecules by
        mass spectrometry
        Don Hunt

10.30   Analysing protein-protein interactions in signal transduction by mass
        spectrometry
        Peter James

11.00   From genomes to "Proteosomes": Expasy and Swiss 2D PAGE
         Denis Hochstrasser
11.30   Building proteins by modular chemical ligation: Exploring a world
        limited only by the imagination
        Stephen Kent


Session 5a:Tertiary and quartiary Structure (A) Crystallography

12.00   Protein structure and recognition
        Louise Johnson

13:30      Analytical Ultracentrifuge Workshop (see below)

17.15   X-ray crystallographic studies on structure and function of
        evolutionarily related vitamin B6 dependent enzymes
        Johan Jansonius

17.45  The structural basis of activation, catalysis and inhibition of serine
       proteases and of the proteasome, analogies and differences
       Robert Huber

18.15   Tertiary structure of the ternary complex containing aminoacyl TRNA and
        elongation factor TU
        Brian Clark

20.00   Challenging the ribosome structure
        Ada Yonath

20.30   Guanine nucleotide dependent conformational changes in Gia
        Stephen Sprang

21.00   3D structure / function studies of acetylcholinesterase
        Joel Sussman


Session 5a: Tertiary and quartiary Structure (B) NMR

21.30   New NMR techniques applied to the study of a conformational switch
        Ad Bax




                        Analytical Ultracentrifuge Workshop
                               Tuesday 30th May 1995



Chairmen:     Dr. Allen Furst, Beckmann Instruments, 1050 Page Mill Road, Palo Alto,
                      CA 34304, USA.
                                          Dr. Todd Schuster, National Analytical Ultracentrifugation Facility,
                      University of Connecticut, Storrs CT 06269, USA.
                      Dr. Richard M. Thomas, Inst. f
r Polymere, ETH-Zentrum, 8092 Z
rich,
                      Switzerland.



13:30   Opening Remarks

13:35   Equilibrium ultracentrifuge studies of complex formation between humman
        gamma-interferon and soluble cellular receptor.
        David Yphantis, Molecular and Cell Biology Dept. and National Analytical
        Ultracentrifuge Facility, University of Connecticut, Storrs , CT 06269-3125 and
        Institute of Molecular Biology and Biotechnology and Biology Dept., University
        of Crete, Iraklion, Crete, Greece.

14:05   Macromolecular solution conformation from hydrodynamic bead modelling
studies.
        Olwyn Byron, NCMH Dept. of Biochemistry, University of Leicester,
        University Rd, Leicester, LE1 7RH, UK.

14:35   Analysis of antibody-antibody and antibody-anti-Fc receptor interactions by
        analytical  ultracentrifugation.
        Steve Shire, GENENTECH Inc, Pharmaceutical R&D Department, 460 Point San
        Bruno Blvd., South San Francisco, CA 94080, USA.

15:05   Interval

15:15   Biophysical characterization of recombinant anti-c-erbB-2 741F8 single chain
        Fv antibody dimer (sFv1)2 and analysis of its interaction with recombinant
        extracellular domain of c-erbB-2 oncogene product by analytical
        ultracentrifugation.
        Walter Stafford, Dept. of Muscle Research, Boston Biomedical Res. Inst., 20
        Staniford Street, Boston, MA 02114-2500, USA.

15:45   Ultracentrifugation studies on the cyclosporin synthetase and the prion protein.
        Detlev Riesner, Inst. for Physical Biology, Heinrich Heine University
        D
sseldorf, Universittstr. 1, D-40225 D
sseldorf, Germany.

16:15   Discussion

16:45   Close




Hope to see you there

---------------------
Richard M Thomas
Inst. f
r Polymere
ETH-Zentrum
CH-8092 Z
rich
Switzerland
Tel. +41 1 632 45 47
Fax +41 1 632 10 73
e-mail rthomas@ifp.mat.ethz.ch